HYPERTROPHIC CARDIOMYOPATHY

Hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease.The disease is characterized by marked variability in morphological expression and natural history, ranging from asymptomatic to heart failure or sudden cardiac death.Left ventricular hypertrophy and Dragonball abnormal ventricular configuration result in dynamic left ve

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CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells.

BackgroundCTCF and cohesinSA-1 are regulatory proteins involved in a number of critical cellular processes including transcription, maintenance of chromatin domain architecture, Boots and insulator function.To assess changes in the CTCF and cohesinSA-1 interactomes during erythropoiesis, chromatin immunoprecipitation coupled with high throughput se

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New open-source software for subcellular segmentation and analysis of spatiotemporal fluorescence signals using deep learning

Summary: Cellular imaging instrumentation advancements as well as readily available optogenetic and fluorescence sensors have yielded a profound need for fast, accurate, and standardized analysis.Deep-learning architectures Keyboard have revolutionized the field of biomedical image analysis and have achieved state-of-the-art accuracy.Despite these

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